Synthesis of some cis-4,4-dimethyl-2-isopropenylcyclopentane derivatives as potential intermediates towards the protoilludane skeleton

Authors

  • SJM Mdachi Chemistry Department, University of Dar es Salaam, P.O Box 35061, Dar es Salaam, Tanzania

Abstract

The three gem-dimethyl-substituted cyclopentane derivatives 1-(2-propionyl)-4,4-dimethyl-2-isopropenylcyclopentane, 2-isopropenyl-4,4-dimethylcyclopentanecarboxyaldehyde and 1-hydroxy- methyl-2-isopropenyl-4,4-dimethylcyclopentane have been synthesized employing a thermally induced ene reaction as a key step. Each of the three compounds has been obtained predominantly as the cis isomer. The successful synthesis of these compounds affords opportunities for their further ellaboration towards sesquiterpenes of the protoilludane skeleton.

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Published

2021-04-18

Issue

Vol. 29 No. 2 (2003)

Section

Articles

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